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Main page > Research and Trials > Swine > Private Research Centre, France, 2005

Private Research Centre, France, 2005

 

 

The effect of ProgutTM on the performance of piglets from 21 to 70 days of age. Private research center, France 2005.

 

Objective

 

The aim of the stufy was to evaluate the efficacy of ProgutTM on piglet post weaning performance from 21 days to 70 days of age under typical French husbandry conditions.

 

Materials and Methods

 

The following treatments were tested in the trial:

 

Treatment Weaner diet 21-42 days Grower diet 42-70 days
A Negative Control - -
B Positive Control
Avilamycine
40 ppm 40 ppm
F ProgutTM 0.1% 0.07 %
G ProgutTM 0.2% 0.1 %
H ProgutTM 0.3% 0.1 %

 

At the beginning of the trial 240 (Large White x Landrace) x P76 piglets were divided into treatments according to sex and initial weight. One treatment was replicated into 6 pens (8 Piglets per pen); 3 pens of light piglets (around 5 kg) and 3 pens of heavy piglets (around 7kg). The number of male and female piglets per treatment was identical. In order to place animals in a sanitary situation as close as possible to field sanitary conditions, pens and watering systems were not cleaned nor disinfected after the previous group. Only faeces and dirt were removed from the floor and drinkers and feeders by sweeping.

 

All feeds were offered ad libitum. Water was supplied continuously via drinkers (1 per pen) from day one until the end of the trial. The trial was divided into two feeding phases: weaner diets from 21 to 42 days of age and grower diets from 42 to 70 days days. The feed was provided in pellet form. The compositions of the feeds are presented in the table below. The negative control group received feed without antibiotics or feed additives (no enzyme, no acidifier and no probiotics). The other feeding treatments had the same basic formula than the control group, but contained the experimental premix of Avilamycine (positive control) or ProgutTM at different doses.

 

21-42 days 42-70 days
Wheat 43 38.2
Corn - 5
Barley 10 22
Wheat bran - 5
Extruded wheat 12 -
Field peas - 5
Toasted soybean grain 12 3
Soybean protein concentrate (HP300) 2 -
Palm oil - 1.2
Soybean oil 0.5 -
Soybean cake 11.38 15.05
Lactoproduct 40% fat 2 -
Lactoserum 2.8 -
Dicalcium phosphate - 0.68
Carbonate - 0.4
Monocalcium phosphate 1 -
Salt 0.31 0.42
Synthetic lysine (78%) 0.56 -
Synthetic lysine liquid (50%) - 0.65
Synthetic methionine 0.12 -
Methionine hydroxy analog - 0.17
Choline chloride (liquid, 75%) - 0.06
Argal - 1.5
Phytase (EC 3.1.3.26) - 0.2
Synthetic threonine (100%) 0.23 -
Threonine (25%) - 0.47
Artificial flavour 0.10 -
Vitamin, mineral premix 1.50 0.5
Experimental premix 0.50 0.5

THE COMPOSITION OF THE TRIAL FEED

 

Piglets were weighed individually at 20, 28, 42 and 70 days of age. All amounts of feeds added to the feeders were weighed as well as remaining feeds in the feeders. Weight gain, feed intake and feed conversion ratio per treatment was calculated between 21 and 42, 42 and 70, 21 and 70 days of age. Health and mortality was recorded daily.

 

All zootechnical data was subjected to analysis of variance, using the UNIANOVA procedure in SPSS 11.0 statistical software. The treatment means were compared using appropriate means comparison procedures. The statistical model included treatment and weight class as fixed effects.

 

Results

 

Feed compositions were anylised in accordance with the expected values, except for the threonine content of the grower feed in ProgutTM 0.3/0.1 % group, which was a bit lower than expected. Mortality in the study was 0.8%

 

Period 21-42 days

 

During the first period of the trial significant differences were observed between the diets for growth performances. The highest growth performances were observed for the positive control diet and for diet H, which contained 0.3% ProgutTM. Feed conversion ratios didn't differ significantly between the treatments.

 

 

Treatment Weight, kg Weight gain g/d Feed Intake g/d FCR kg/kg
A Negative Control 11.01bc 239.5bc 302 1.27
B Positive Control 11.82a 277.9a 334 1.20
F ProgutTM 0.1/0.07 % 10.65c 222.4c 292 1.30
G ProgutTM 0.2/0.1% 11.19abc 247.8bc 310 1.26
H ProgutTM 0.3/0.1 % 11.48ab 262.7ab 325 1.27

PERFORMANCE FROM 21 to 42 DAYS

abc values with different superscripts differ statistically (P<0.05)

 

The figure below shows the correlation between performances and quantity of ProgutTM ingested per day. According to the weight gain equation the optimal dose of ProgutTM per piget per day was around 1g. This is close to an addition of 0,3% ProgutTM in the feed during this period (feed intake 300 g/day x 0.3% ProgutTM in the feed = 0.9g of ProgutTM/piglet/day.

 

THE CORRELATION BETWEEN PERFORMANCE AND QUANTITY OF PROGUTTM INJECTED PER DAY

 

Period 42-70 days

 

Both the growth and feed conversion ratio in treatment G (ProgutTM 0.2/0.1) and positive control were significntly better than in the negative control group. Also piglets in group H (ProgutTM 0.3/0,1%) performed numerically better than the negative control but the differences weren't statistically significant.

 

 

Treatment Weight, kg Weight gain g/d Feed intake g FCR kg/kg
A Negative control 26.11bc 537.8b 937 1.77b
B Positive control 28.01a 580.5a 995 1.68ab
F ProgutTM 0.1/0.07% 25.72c 536.1b 924 1.72ab
G ProgutTM 0.2/0.1% 27.90a 591.4a 979 1.66a
H ProgutTM 0.3/0.1% 27.24ab 568.8ab 990 1.74ab

PERFORMANCE FROM 42-70 DAYS

abc values with different superscripts differ statistically (P<0.05)

 

Period 21-70 days

 

During the whole trial period group G and positive control had significantly better growth and feed conversion than negative control. Also piglets in the H group performed numerically better than the negative control but the differences were not statistically significant.

 

 

Treatment weight, kg weight gain g/day feed intake g FCR kg/kg
A Negative control 26.11bc 410.5bc 670 1.65b
B Positive control 28.01a 453.9a 716 1.57a
F ProgutTM 0.1/0.07% 25.72c 400.1c 658 1.63ab
ProgutTM 0.2/0.1% 27.90a 447.6a 697 1.56a
ProgutTM 0.3/0.1% 27.24ab 432.5ab 710 1.63ab

PERFORMANCE FROM 21-70 DAYS

abc values with different superscripts differ statistically (P<0.05)

 

The ProgutTM intake per day was calculated and the correlation between ProgutTM ingestion and performance was studied. The equations below enabled to calculate and optimum daily dose for growth and feed conversion ratio of 0.9-1g of Progut/day/piglet.

 

 

Conclusions

 

- During the total trial period from 21 to 70 days of age, ProgutTM, at two higher doses improved the piglet performance in comparison with the negative control group.

- The improvement in performance was positively linked to the dose of ProgutTM ingested per day

- The optimum dose of ProgutTM for the whole trial period was identified to be 0.9-1g of Progut/piglet/day

- The optimum dose corresponds to 0.3% of ProgutTM from 21 to 42 days and 0.1% of ProgutTM from 42 to 70 days.

 

 

 

 

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